Richard Friedman, MD, has recently written an article in the New York Times on our troubled relations antidepressants. He opens his article asking how antidepressants may affect psychological development and patient identity database.
This is an interesting question, some were discussed in the past, but worth another attempt.Unfortunately, Friedman Explorer of this question.Ce that it Explorer, however, is the difference between what we know about the drugs, and what we don't know: scarcity of long-term efficacy study and long-term safety studies.
On the one hand, he observes, there is almost no good effectiveness study spent two years terminaison.Et point a brief commentary on warning on suicidality, where it considers that the risk of suicide is actually small enough, the risk of the disease is greater. Suicide, he wrote, is the third leading cause of death among youth.
Friedman follows the ambivalent model many psychiatrists muse on their land. It offers one or two paragraphs on the benefits of antidepressants, followed by another on risks or unknown.And mandatory on requiring more data, requiring better monitoring.
SSRIS are the most studied class of drugs in the history it was more studies, data and Yes, more followed, to something that other SSRIS. In addition, it is more debate, both in psychiatry and the general public on the effects of these drugs - not only in biological terms, but socially and whose existence is.
The problem is, that Friedman, insufficient information. The problem is the opposite: too much information and too little context.
The question is not "do they cause suicide." The question is: a pill can interfere with complex behavior? If it can cause suicide you, why does it cause you to bake a cake? How a pill cause a series of complex behaviours occur resulting in suicide? Or, conversely, how a pill changes your mind want to do?
The question is not "are antidepressants better than placebo for treating depression?The question is: that means "treatment for depression?A simple example is that most SSRIS are tested against a scale (e.g. HAM - D) which has three (17) questions about insomnia, but none on Hypersomnia.Is it conceivable that a drug may treat insomnia and thus consider artificially good treatment of depression?Or better than something that treat insomnia?You bet.
Most psychiatrists will agree that depression that results from not clear cause, "" I have nothing to depression, but I'm "") differs from depression due to a cause (e.g. divorce.)Surprisingly, there is however almost no study differentiate the efficacy of a drug in these two scenarios, whether Zoloft is preferable for depression divorce for the non-raison depression; or if the Prozac Zoloft divorce better, depression, etc.Tout is regroupée.tous depressions are the mêmes.tous SSRIS have the same efficacité.Il is almost never asked if consistent efficacy of SSRIS is not due to the fact that that they are all tested against the same scales; and if the new had been invented (e.g. a Hypersomnia questions) some SSRI would be "better" than others.
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